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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f106dad5f261fc3bd92646491b3bc2c4d1c566e8bf1f60e656ab1723f1520944' 
  AND token = 'fzz9KDMCdDpkWdDhdZqBor9g5RoUMnWaVnQKAq475HY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}