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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '661bfe69b170c35360b65a46105595add41a9a744709f34295d278571aa2ff3d' 
  AND token = 'XG9xGM8k0tbhiWJIsX18rM3u7nPkOoEBGcq9bNrrZks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}