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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '455df4f572a59c9c3a60487f5f59b4a527b7181fc8ed0d28d08467164026158c' 
  AND token = 'zdnrtrWrFAjfv258Y2gitoVB8TAd1cvkKZqHi2wmbtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}