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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1ed83b0125d2b7e896938f6815f4997317c1789cf2ce636d591cf8d552eb32e2' 
  AND token = '7W1XRAdJcQPDfKpIs3NgQc0axIQ/aYnOOuwxMq6XCWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}