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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1859ec85f91ca50697e1859c46e8744f496d7fdb4936fd97fb6bc86c3173412c' 
  AND token = '8BRhrYxIL70LelxNRaLGAY6qbD6Bqm/Ldd5Tu++grMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}