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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a50cdd783673c01c1266d70665f4a60cf42ebb3828667b7e132b788c79c3fe1d' 
  AND token = 'MA6s9eIeHlklBQCJiWV/Il7pr4FSeI2qEE2hYnkl8CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}