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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4999ef61a12b2982a15dc4e59824f42fe1802b026991ccd44489458ccc05d20a' 
  AND token = 'K+uD5FdTkO+FN3EulhS3gHVoFIFMqs8uBwiaDEoiCWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}