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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '324933ecd4a1af68220c0ba1361c9e10cc4b2aec96165e45e019f936d40696c0' 
  AND token = 'WGRB573wOjwEij6yDhpPvsaNaUyHm8SWv9qbdAERZtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}