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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10a5d2766ad4b143204c8d36d3d55d2a3d770f1996f961d0a5160beeb4abaf12' 
  AND token = 'dy+9HS77qTgn4uRCWnUqGl1k03HlBig9T6zQ0qLkeoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}