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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dee564d2e535da6ad99ce26d0b4d3579371fda01e36205b1c0c4b00161bf42b7' 
  AND token = 'vsGCcpayvHXrfaRqOWOr+UWqx5VD7zvIR9kEOeIq2wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}