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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65ab43dc34fb7aa7e2e703e1a904f29811b70aa42970350ea293b392df4a1438' 
  AND token = 'yolKOYnjpxeKfBpnIMHXdnPmiNLk4WaQoWogQxyl4Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}