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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '368333ec58fc9fa2d7f1fd38abe0072c633b679621f18584ae039ad49ab826a3' 
  AND token = 'IKkPEIQ6a4c/iKRs9mg3k24iEURab43jGjBXB265Lt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}