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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1a9f6344cd99a9371026e281b319cd9a4cbd328258b0d7410345fb75f52d1b69' 
  AND token = '4iXbHWn5s0BvrbRMZnARYJwjI1R7aeEdrQX75qeD0Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}