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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8f0a90526121e6e4de39718b39e74512c6cb278dfd453fd6c669b8960078e38f' 
  AND token = 'txZdfsAlm7jcC+HjyxdbG82vGdVa9vv3QVlFvP+Ha0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}