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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e1c636f6fac362d3020647b327c052a8db0e34a7921318e02243f1c218ffa91' 
  AND token = 'uP1mRxJxG3lw15ROrJdDewAcuwPTPOqTY1C1txc5hUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}