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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '35ecc0fdfb8d4b549ea1901501fd3597c7370c3c20b3833507c0884977bf270d' 
  AND token = 'ftmBQwqMXOILHeTlWuuU6ykXZKyt+Hgbae6GaM5rfzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}