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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ef09738be5427f78ef009a7e85869265224dde671f114bda5056a33d17f42601' 
  AND token = 'UMCdhY5TzrFF4gWUMgdo8wCLi7OF8TCetIVQnSppkLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}