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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c6e61558b3fe09f320290a7ca9344511b6be43044298119b04622a2b6dc7b05f' 
  AND token = 'gP2krC4p4bz3as1+1rWH4SVMTQdWVBZok2JJoGKf8ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}