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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '52d64ef6e3257125fd464c11206fe341ef8348c5d49da64e52c48f3a9e061f7e' 
  AND token = 'V1kGjgJIpnEr/0FoRbyAMCekI7/IQJAsJldb3ioQLgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}