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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65ca8e46bed4586e178ba6ec2f64b2d27e102ce8744af19bb2bfce4ea7859a49' 
  AND token = 'kFbHT453U9z7SjvkbJd5XFQftuM9DbhIUQ1qv3DoO3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}