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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0d9052ed61b5e110d46e6049c2731278bc5156779313341beba94caf5e6bc059' 
  AND token = 'IYaD+pOnQsAMVqXNpSLMf8x2WruoLSuD8mOz5oJR9b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}