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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9403b96cbd77628d49bd2f0f807b16e2bebe5dcb392857b484d5656e779ff6bb' 
  AND token = 'dEJTGaWEVhAmkhBrgXVfoIuf3BfcauPkgZaHH4a3mX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}