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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e6b454a2fa1820de9d863b9ddb530dbd12641fd7577bdcf555e5023a640521a' 
  AND token = 'YuVvXcsVLCcpYsl1rWiYKlXUMd4zZWSY+VD8rCc/cbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}