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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b36d11bd2d4476270a99a5b95fc185ebebfd65d5e3b15ee9e58296106b96e481' 
  AND token = '+2SNDCqqk3fkiiE63Kh7hK828qIMszbbRtH4uJ5UaiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}