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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '101f59e2e9e0a1d16f7f35e7e8eb2be918f5cfa936667cac5e5e99aebf00ac69' 
  AND token = '+XRGEo5WtrIDSwjOLZlmH/JUKxlPp9kqVdLtQlxxMVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}