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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'caf85b2d6c20df666437171d8fb968574c182ec4bc68317ade9bc34219397093' 
  AND token = 'BB1OweACopz8pxhc854zFRHjAG+AipyOfo1OCOrJphk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}