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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ac24a1215cb1865eb72ad22f99f9e417a65e79f82eaad766ed97709485d5183a' 
  AND token = 'f7CkzsL+A+/UAiYAwE0h2Vpwl7TRo3YMj7V79eDtLWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}