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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cf8f3458b3642e0310cad2a6aed2cd2bd515acdfbe89162d0bbe1ce5bf1a3801' 
  AND token = 'wrTO6tJTZ8EyydaMqJQhgBmN4fq/zQVOIJrTz5Hosx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}