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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3b0cf81bc3eb8492213c12fc7232af4bf94f25572a26cbeb1b1605dd6e7169ae' 
  AND token = 'icF2xSQ/xwvBxCL1pZAEiguxXBtJIbmQ1ykzNSMfO+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}