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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46637560871f04b44fc6e3f92d81b0cbfa47f56f038677d51e12010ecbc4e030' 
  AND token = 'W32eaWzIFS9UqE8FYEO4l4xO/VxiNQXadRU9ssiNX7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}