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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a2b9a92b5738ec20d90bbfa4b0cd8491db6d3d8f4caabe2fde18edbb66c78f21' 
  AND token = 'NJjtaq1bkTpjW4sn1hPEQzz2uspM1cKT4CDtfHZiUaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}