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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '429f4b1970d259d1467e60c75280276e803f46771a713c3cb62f959987f15e4f' 
  AND token = 'CQHiE+XRZkl4JeEb6JjnjdpRhkyT/0fAG0omQE+Aj6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}