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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f45680ea4b83d2ec8b96649bd78d214f013f5e90d3d8b9715c34624cff726463' 
  AND token = 'rwFIB3X7CO7tq+qEazIr3LU39EtmLeZHwMxNhxS3okA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}