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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '307c19fee2fc3a14fbc9f9e14de9b991daff021888a8f43026f96922dec2d99c' 
  AND token = 'DbQx55vpADE7vhVwEqAsahv34mbmzt8yFiwjq7ZK16Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}