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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5380fe963b21a9b616b5a9fefe7facdf435d18cc2c7933f47c191e925250b397' 
  AND token = 'EoVafnZuxA5MXS+QYaUpUUBF1QhDN84HhmXDdt3xMgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}