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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '11998a24c5e82cf98e4a9498333a8ad680ce51f7a2b499a1dab4c5079454a4cf' 
  AND token = 'OlR//pfaay37Wm02fAZisz7HlOsds4WmNsrrLRzolbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}