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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '41ac54b88debcea2e99ed641256895988b732e1810f9dd3ff6124300c5754371' 
  AND token = 'jX8dhOmxrVgRv8jya6silWG3K3s8xptHk9ye4eBxnHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}