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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e0552fc58489e7b372c233baec2f2e13ead07b4f0d85bc6e03d85fd048ae3367' 
  AND token = 'ZpXF4jopWpGx8bD+iMFt5y322nOJllssdR0PDKvinRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}