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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5e8ed4eace5ea1c09b42f8d86910c42eb07b8c7d3d1eb023f3e55e5aa5b8f8da' 
  AND token = 'qUeZOaOWdc6gTM8oCS+BTcqLiQak82mZtaIMeQmsn4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}