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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f7bade831970c754ff8bb81e46b43bbdfe8ae1d621d1d605b1fc854107a16432' 
  AND token = 'uCOWY9yI+LKfgIItiF6PnGxiBoHpGuZmrcnSor8++eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}