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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c6d1c3385d1ef1b030ae182e0260771650685f54db2e6201200a147e4f47af9' 
  AND token = '+WHJh0MpPIymmeuRB5palf+AUxYGYDoE3UyQZ/O1eAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}