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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49ad6ae11e8c7d02f335c206a8f287cd05a43ff807a4f8c490120f1e84757446' 
  AND token = '4srDT+gshw5ddUPLnLFtBlsus95rSH2SNTc5qWR22CQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}