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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6c3ab9020c40db9345f09e7b49b903d27b0b41e0a01819abcfb54d96c442d99f' 
  AND token = 'MZn97nyVFXNgyGacN632+zMqb5GZmZd4Afsx4a71FFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}