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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05d3b826c7c4f19ccd73c1206ecf36dbd910e6474fa2589557d72b634400f6aa' 
  AND token = 'sutorREBZfLXOdz22SLNpx68/wktfupM7IIEtsRHcUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}