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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6e19867f446a907d3aca5c06ef8b66dbce20d7cfbdca93a1c8d067779d40e22f' 
  AND token = 'mJ2Fs9Uu4qSWTfsTdKCIh4/6sQjBnsysPNMF0Pbkb0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}