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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '267021c0e727a385b191f6418bc9bb785d7699eb22c60e8b3756ee143b154e3f' 
  AND token = 'uIPnqn232Sy64E7nxEc8yI+s4RmBwown9GExZUfuxJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}