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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43e955b631c3e1f68b67cf89d139e3430487639f5cc50f43d193fa8c975e0277' 
  AND token = 'hSMyTehaiw6pWiX5cY6o4OC+kabtB0/0lX0aQFJ++2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}