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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '414dda9733bf5688bb014b33c407dd10b0d0d7a52ace59c8eda265a27d8e7be0' 
  AND token = 'zu01mEfqelHkCI00uQoOfC55i94jlfLhsuGhc6GYP3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}