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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a15def623a346536bac5134095c1d329ac6178b883e2182da06d80448fdb964d' 
  AND token = 'XBjnOd4I0/Ev2mgdOs+p38Blx32dBgzNJpxGkNk5NoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}