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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45ec4dba523637a46e1571273fcfef75aefdbb0dd5f3241a9b84f14109d23a11' 
  AND token = 'HOHbuMBXTUQ1YqRjQPYx0HCeE8GW1L9MatmcR3XJxBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}